Digital life coaching during autologous cellular therapy for B-cell malignancies
Several B-cell malignancies (BCM), including multiple myeloma (MM) and non-Hodgkin’s lymphoma (NHL), may be treated with high-dose chemotherapy followed by autologous cellular therapies such as stem cell transplantation (SCT) or newer modalities involving chimeric antigen receptor (CAR)-transduced cells. Both therapies entail extensive life disruptions that lead to long-term depression, anxiety, or insomnia in up to 1/3 of survivors. Complications of these negative symptoms include quality of life (QOL) impairments, post-trau