Rationale: Currently, there is no direct pathway for health sciences research to move from scholarly publications into policy and law. Although some evidence is cherry-picked by advocates and policymakers, legislation often reflects rhetoric rather than evidence. While some translational researchers study the effects of laws or write white papers summarizing the state of the evidence, we know of none who take the approach of working with investigators to leverage their research and write model legislation.
An Open Proposal Opportunity
Most Commented Proposals
Rationale: The purpose of this application is to strengthen the tuberculosis (TB) translational research capacity at UCSF/SFGH by developing a BSL-3 laboratory in which work with human TB can be safely carried out in tissue culture and in small animal models.
Rationale: Enrolling subjects for longitudinal research studies, ensuring their compliance and retaining them over a period of time pose a significant challenge to researchers. As an example, we had 62% and 30% retention at years 1 and 3 in a recently concluded study on knee osteoarthritis.
Rationale: The APEX system has been promoted to the faculty as providing a new and extremely valuable means of doing clinical research, especially for discovering previously unappreciated clinical associations such as the relationship of kidney stone and myocardial infarction, etc.. Such associations would be very valuable in discovering underlying mechanisms of disease. However, the APEX system falls very short of fulfilling this promise, because it has been primarily designed for maintaining information for medical practice, and for billing. The problem is that it forc
CTSI’s Consultation Services Data Management Unit (DMU) is just one of the successful research resources available on campus to help UCSF faculty and staff with his/her research. Along with many other data management services, the DMU also provides consultation in data processing to help transform research data into a statistically analyzable format. In our efforts to provide consultation to the UCSF research community, we have realized that some trainees and faculty do not have the programming skills or resources to perform data processing tasks that are necessary to keep their research moving forward. Complicated data merges and transformations require specific programming expertise to ensure that it is performed correctly. Data management programmers, who can devote more time and effort to small projects, are needed. The DMU’s ability to provide these services is very limited. As a result, we have identified a gap in services that the Data Management Unit is currently able to provide.
Rationale: The confluence of online social media, smart phones, and sensor technology is giving rise to a tidal wave of digital health interventions that have vast potential for improving health at low cost. As with consumer software, digital interventions are more likely to be effective if user feedback and determination of effectiveness is sought early and often. At present, however, researchers face high costs and difficulty in developing app ideas into prototypes, testing prototypes on real users, and validating the intervention.
Title: $15,000 a dose: A patient-centered study of drug development and research
Rationale: UCSF and the Benioff Children's Hospital have been selected by the national Children's Oncology Group Consortium (COG) of the National Cancer Institute (NCI) to conduct new Phase I Pediatric Oncology studies. Patients enrolled in these studies who are not admitted to the Pediatric Clinical Research Center (PCRC) Inpatient Unit, will require evening and weekend support for study procedures, including timed blood draws, sample processing and EKGs.
1. Rationale – the science of operations.